Thursday, August 7, 2008

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NIH Grants Will Fund University Of Wisconsin Stem Cell ResearchThe National Institute of General Medical Sciences recently awarded an $8.9 million grant to a team of researchers from the University of Wisconsin-Madison to investigate the "fundamental power" of human embryonic stem cells, as well as cells that have been "reprogrammed" to function like embryonic stem cells, the Milwaukee Journal Sentinel reports.Recipe For Cell Reprogramming Adds Protein - Embryonic-Like Stem Cells Can Be Created Without Cancer-Causing GeneA drug-like molecule called Wnt can be substituted for the cancer gene c-Myc, one of four genes added to adult cells to reprogram them to an embryonic-stem-cell-like state, according to Whitehead researchers. Researchers hope that such embryonic stem-cell-like cells, known as induced pluripotent (IPS) cells, eventually may treat diseases such as Parkinson's disease and diabetes.New Insights Into The Development Of Epithelial Cells - MDC Researchers Discover More Diversity Than ExpectedEpithelial cells cover all internal and external surfaces of the body. They have an upper and a lower side, which have different functions. Until now, scientists assumed that these two poles develop in all epithelial cells in the same manner - irrespective of whether they are located in the heart, in the retina, or in the nervous system. Now, Dr. Nana Bit-Avragim, Dr. Nicole Hellwig, and Dr.Five Bush Administration-Approved Stem Cell Lines Used Insufficient Consent Forms, Bioethicist ReportsInformed consent forms for nearly one-fourth of the human embryonic stem cell lines approved for federal funding by President Bush in 2001 could present serious ethical problems, according to a report published in the journal Hastings Center Report, theNon-Healing Bones Repaired In Clinical Trial Using Adult Stem CellsThe Royal Melbourne Hospital and Australia's regenerative medicine company, Mesoblast Limited (ASX:MSB)(PINK:MBLTY), jointly announced successful results from the long bone fracture repair clinical trial using Mesoblast's proprietary adult stem cell technology. Ten patients with a total of 11 non-healing fractures of the long bones in the legs (following road trauma in 8) were operated on using Mesoblast's proprietary stem cells.Boston Globe Examines Debate Concerning Usefulness, Expense Of Storing Umbilical Cord BloodThe Chicago Tribune/Boston Globe on Thursday examined the debate concerning the potential benefits for pregnant women to store umbilical cord blood. According to the Tribune/Globe, there are more than 24 companies that offer storage of cord blood for a fee.Mich. Board Sets Hearing To Decide If Measure Loosening Stem Cell Research Restrictions Will Be On BallotThe Michigan Board of State Canvassers on Wednesday scheduled an Aug. 21 meeting to review signatures submitted for state ballot initiatives, including a proposal to loosen state restrictions on human embryonic stem cell research, the AP/Lansing State Journal reports. The board also set an Aug. 13 deadline for opponents to challenge sample signatures.NY Stem Cell Foundation Plays Critical Funding Role In Major New ALS ResearchIn a breakthrough discovery, Dr. Kevin Eggan, Chief Scientific Officer of The New York Stem Cell Foundation and Principal Faculty Member of the Harvard Stem Cell Institute, has produced human stem cell lines from the cells of patients afflicted with a version of amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease. Eggan's work marks the first time scientists have replicated in a laboratory the specific human cells affected by disease.Research Team Creates Human ALS Motor Neurons: First Disease-Specific Stem Cells From Human Skin CellsA team of researchers from the Harvard Stem Cell Institute (HSCI) and Columbia University, in a collaboration catalyzed by the Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, has demonstrated that pluripotent stem cells generated from a patient with ALS (amyotrophic lateral sclerosis) can be directed to differentiate into motor neurons - the very brain cells destroyed by ALS. The results of the team's study appear in the online issue of Science.Stanford Fruit-Fly Study Adds Weight To Theories About Another Type Of Adult Stem CellIt turns out that an old dog - or at least an old fruit-fly cell - can learn new tricks. Researchers at the Stanford University School of Medicine have found that mature, specialized cells naturally regress to serve as a kind of de facto stem cell during the fruit-fly life cycle. The surprising discovery counters the common belief that the ability to form new cell types or tissues wanes as a cell becomes more specialized.
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