Beating Heart Created In LaboratoryUS scientists have for the first time made a beating heart in a laboratory using heart tissue from dead rats and pigs to make a framework and seeding it with live cells.The research is the work of scientists at the University of Minnesota and is published in the January 13th early online issue of Nature Medicine.Bone Marrow Cancer Made Resistant To Treatment By Stem CellsScientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and have multiple ways of resisting chemotherapy and other treatments.A report on the evidence, published in the Jan. 1 issue of the journal Cancer Research, may explain why the disease is so persistent, the Johns Hopkins scientists say, and pave the way for treatments that overcome the cells' drug resistance.Improved Understanding Of Niche Control Of Stem Cell FunctionThe Stowers Institute's Xie Lab has published findings that begin to characterize the poorly understood interaction among stem cells within their cellular microenvironment, called a niche.The findings appear in Cell Stem Cell.The Xie Lab demonstrated that differentiation-defective Drosophila ovarian germline stem cells (GSCs), behaving like human cancer stem cells, can out-compete normal stem cells for a position in the niche.Advanced Cell Technology Announces Creation Of Human Embryonic Stem Cell Lines Without The Destruction Of EmbryosAdvanced Cell Technology, Inc. (OTC Bulletin Board: ACTC) together with colleagues announced today the development of five human embryonic stem cell (hESC) lines without the destruction of embryos. These new results have the potential to end the ethical debate surrounding the use of embryos to derive stem cells. In fact, the NIH report to the President refers to this technology as one of the viable alternatives to the destruction of embryos.New Insight Into Factors That Drive Muscle-Building Stem CellsA report in the January issue of Cell Metabolism, a publication of Cell Press, provides new evidence explaining how stem cells known as satellite cells contribute to building muscles up in response to exercise. These findings could lead to treatments for reversing or improving the muscle loss that occurs in diseases such as cancer and AIDS as well as in the normal aging process, according to the researchers.DomaniCell's Unique CGMP And Hospital-based Cord Blood Program ExpandsDomaniCell, LLC (DomaniCell), a leading service provider in the field of stem cell collection and storage, announced that Saint Peter's University Hospital has recently partnered with DomaniCell to provide a hospital-based cord blood banking program.Scientists Urge Embryonic Stem Cell Research; Despite New Technique Creating Embryonic-Like Stem CellsAlthough some experts "hailed" the November 2007 announcement that scientists in Japan and Wisconsin had "reprogrammed" mature adult human skin cells to produce embryonic-like stem cells that might eventually be converted into heart, nerve or other tissue as the "solution" to the U.S.Differentiation Blocked In Tumor Stem CellsA new comparison of normal stem cells and cancer stem cells reveals that the cancer stem cells are abnormally trapped at an early stage of development. The research, published by Cell Press in the January issue of Cancer Cell, significantly advances the understanding of glioma pathophysiology and provides new directions for design of therapeutic strategies that are targeted to specific types of tumors.Growing Artificial Skin From Hair RootsThere is new hope for patients with chronic wounds: euroderm GmbH and the Fraunhofer Institute for Cell Therapy and Immunology IZI in Leipzig have been granted approval to produce artificial skin from patients' own cells. It sounds like something from a science fiction novel: Pluck a few of someone's hairs, and four to six weeks later they have grown into a piece of skin.Strong Support For Embryonic Stem Cell Research Declines, Overall Support Remains Stable, Poll FindsStrong support for human embryonic stem cell research has declined nationwide from 27% in 2005 to 21% in 2007, but overall support has remained stable at about 54%, according to a survey released late last month by Virginia Commonwealth University, the Richmond Times-Dispatch reports.Cardiac Stem Cell Therapy Closer To RealitySince the year 2000, much has been learned about the potential for using transplanted cells in therapeutic efforts to treat varieties of cardiac disorders. With many questions remaining, the current issue of CELL TRANSPLANTATION (Vol.16 No. 9), The Proceedings of the Third Annual Conference on Cell Therapy for Cardiovascular Disease, presents research aimed at answering some of them. Eleven papers were included in this issue; the four below represent a sample.
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